Global stability and periodic solution of the viral dynamics

It is well known that the mathematical models provide very important information for the research of human immunodeficiency virus-type 1 and hepatitis C virus (HCV). However, the infection rate of almost all mathematical models is linear. The linearity shows the simple interaction between the T cells and the viral particles. In this paper, we consider the classical mathematical model with saturation response of the infection rate. By stability analysis we obtain sufficient conditions on the parameters for the global stability of the infected steady state and the infection-free steady state. We also obtain the conditions for the existence of an orbitally asymptotically stable periodic solution. Numerical simulations are presented to illustrate the results.     

Existence for bounded positive solutions of Schrödinger equations in two-dimensional exterior domains

In this paper, by using the fixed point theory, under quite general conditions on the nonlinear term, we obtain an existence result of bounded positive solutions of Schrödinger equations in two-dimensional exterior domains.     

Cauchy problem in the class of monotone increasing functions

The paper establishes some solvability conditions of the Cauchy problem for linear differential equation in the class of monotone increasing functions. The results are applied for clarifying the possibility of flight along a given trajectory under existence of braking forces.     

一类椭圆型方程的多重解

利用极小极大方法获得了一类Dirichlet问题多重解的存在性结果.     

关于半线性热方程整体解的注记

利用Besov空间的热核刻画及压缩映射原理,研究半线性热方程ut-△u＝u|u|a的初值问题,得到了当初值u0∈Lp0(Rn)且||u0||(B·)p-n (1/p0-1/p),∞(Rn)(p0＝na/2,p＞p0)充分小时,整体解的存在性及在一定条件下解的惟一性.     

关于《一类奇异边值问题的正解》的注记

文[4]通过构造反例断言文[1]中定理的必要性证明有误,本文首先指出文[4] 的这个断言不正确,然后对文[4]中定理2.1作了本质性的改进.     

Existence and Life Span of Periodic Solutions for the First Order Quasilinear Hyperbolic Equations

g1.IntroductionWeconsiderthefollowingfirstorderquasilinearhyperbolicequationswithinternaIdissipa-tlveterm:U, A(U)U. F(U)=o(1.1)whereUeR2isunknownvectorfunction,A(U)is2X2knownsmoothmatrix,F(U)is2X2knownsmoothvectorfunction.Itiswell-knownthatCauchyproblemoftheequations(l.1)hasbeenwidelystudied(Ll-6J),however,theequations(l.1)withperiedicinitialdatahasbeenhardlystudiedandonesfindthatitiscomplicatedforproblemwithperiodicinitialdata.Becausetheperiodicdis-turbanceLlirectlyinfluencesthebounde…     

Size exclusion chromatographic determination of hydroxypropyl methyl cellulose and polyethylene glycol 400 in an ophthalmic solution

Summary Hydroxypropyl methyl cellulose (HPMC) and polyethylene glycol 400 (PEG 400) content in HypoTears™ Daily Dose ophthalmic solution are determined simultaneously by size exclusion chromatography. The retention times of HPMC and PEG 400 are 10.6 and 15.4 minutes, respectively. The method requires minimal sample pretreatment and is accurate and reproducible. The peak area response from a refractive index detector versus HPMC and PEG 400 concentration is linear over the range of 50–150 % of their label claims of 2.5 mg/mL and 10 mg/mL, respectively. The mean absolute recoveries of HPMC and PEG 400 at their label claim using the described method are 98.9±1.3 % and 100.4±1.2 % (mean±SD, n=12), respectively.     

Metastability of a circular o-ring due to intrinsic curvature

An o-ring takes spontaneously the shape of a chair when strong enough torsion is applied in its tangent plane. This state is metastable, since work has to be done on the o-ring to return to the circular shape. We show that this metastable state exists in a Hamiltonian where curvature and torsion are coupled via an intrinsic curvature term. If the o-ring is constrained to be planar (2d case), this metastable state displays a kink-anti-kink pair. This state is metastable if the ratio is less than , where C and A are the torsion and the bending elastic constants [#!landau!#]. In three dimensions, our variational approach shows that . This model can be generalized to the case where the bend is induced by a concentration field which follows the variations of the curvature. Received: 27 August 1997 / Revised: 23 October 1997 / Accepted: 12 November 1997     

A Class of Cauchy Problem for Quasilinear Hyperbolic Systems with the Weakly Dissipative Terms

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